Journal of Medicine and Health Technology
Journal Of Medicine And Health Technology An open-access, peer-reviewed journal publishing original research and reviews in medicine and health technology, advancing insights and solutions for medical professionals and researchers worldwide. Submit Your Manuscript About Our Journal Advancing innovative medicine and health technology research to inspire solutions for professionals worldwide. E-ISSN: 3046-6865 Focus and Scope The Journal of Medicine and Health Technology (JMHT) publishes original articles, case reports, and review papers focused on medicine and health technology. It aims to provide medical professionals, engineers, and researchers with new insights and practical solutions in diagnosis, therapy, and prevention. JMHT is an open-access, peer-reviewed journal that ensures fast publication and widespread global access. We welcome quality contributions, including theses, dissertations, research papers, and reviews, to advance knowledge in the field. First published online in May 2024, JMHT releases issues biannually in May and November. Detailed Scope
Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember
Breath Smoke Detection: Non-Invasive Assessment of Substances Found in Cigarettes
Breath analysis not only holds great potential for the development of new non-invasive diagnostic methods, but also for the identification and follow up of drug levels in breath. This is of interest for both, forensic and medical science. On the one hand, the detection of drugs of abuse in exhaled breath-similar to the well-known breath alcohol tests-would be highly desirable as an alternative to blood or urine analysis in situations such as police controls for drugged driving. Despite the many benefits and conveniences offered, the use of this useful tool is currently still very rare and requires shipping from abroad. Development is needed to realize it in a more affordable version, so researchers discuss further in this paper
Copyright (c) 2026 Journal of Medicine and Health Technology https://creativecommons.org/licenses/by-nc-sa/4.0
Hypothermic Perfusion Effects on Corneal Endothelial after Phacoemulsification
Phacoemulsification is the most common cataract surgery performed as an efficient and safe cataract surgery technique compared to other cataract surgery techniques. Indeed, phacoemulsification uses high-intensity ultrasound energy to fragment and emulsify the lens, which can cause trauma to the cornea, especially the endothelial layer. Surgical trauma to the CEC can have severe complications on functional outcomes such as decompensation, leading to corneal edema with visual impairment and irreversible bullous keratopathy. The application of hypothermia is known to have a protective effect on various cells and tissues, so hypothermia perfusion is considered to protect the corneal endothelium during phacoemulsification procedures. Hypothermic perfusion can be used to reduce corneal endothelial cell damage during phacoemulsification procedures.
Phytochemical Constituents and Therapeutic Potential of Pine Bark and Needle Extracts in Cardiovascular and Metabolic Disorders
Cardiovascular and metabolic diseases remain leading global health challenges, necessitating novel and complementary therapeutic strategies. Natural plant-derived compounds, particularly from pine bark and needles, have attracted attention for their potential health benefits. This study aims to comprehensively review the phytochemical composition of pine bark and needle extracts, focusing on their biological activities and potential roles in preventing and managing cardiovascular and metabolic disorders. A literature review was conducted using databases such as PubMed, ScienceDirect, and Google Scholar, focusing on studies published from 2000 to 2024. The selection criteria included in vitro, in vivo, and clinical research articles investigating the phytochemical profiles and pharmacological effects of pine bark and needle extracts on cardiovascular and metabolic health. Pine bark and needle extracts, especially from Pinus pinaster, are rich in proanthocyanidins, flavonoids, phenolic acids, stilbenes, and terpenoids. These bioactive compounds exhibit potent antioxidant, anti-inflammatory, and endothelial protective properties. Clinical and preclinical studies demonstrate improvements in blood pressure, lipid profiles, glucose metabolism, and vascular function. Emerging evidence also suggests a role in modulating gut microbiota, contributing to systemic metabolic benefits. Pine bark and needle extracts hold significant promise as adjunct therapies for cardiovascular and metabolic diseases through their multi-targeted mechanisms. Further well-designed clinical trials are necessary to validate their efficacy, optimize dosages, and ensure safety for broader therapeutic application.
Enhancing Gut Health: Probiotic Interventions in Preterm Neonates with Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) remains a significant challenge in neonatal care, particularly in preterm neonates, due to its high mortality and morbidity rates. Probiotics, defined as live microorganisms that confer health benefits to the host, have emerged as a promising intervention to enhance gut health and reduce the risk of NEC. This study aimed to evaluate the role and efficacy of probiotic interventions in preterm neonates with NEC by analysing existing literature and clinical studies. Data on the types of probiotics used, their mechanisms of action, dosage regimens, and clinical outcomes were extracted and analysed. The findings revealed that specific strains of probiotics, including Lactobacillus and Bifidobacterium, significantly reduced the incidence of NEC and associated mortality in preterm neonates. Probiotics were found to modulate gut microbiota, enhance mucosal integrity, and reduce systemic inflammation, thereby mitigating the pathogenesis of NEC. The study also highlighted variations in the efficacy of different probiotic strains and dosing strategies, indicating a need for standardized protocols. The results underscore the potential of probiotics as a preventive and therapeutic tool for NEC in preterm neonates. Future research should focus on identifying optimal probiotic strains, dosages, and long-term safety profiles to establish robust clinical guidelines and improve neonatal outcomes.
Anesthetic Agents and Mitochondrial Function A Comprehensive Review of Cellular Bioenergetics and Clinical Implications
General anesthetic agents have traditionally been understood to function by modulating synaptic receptors. However, emerging evidence highlights mitochondria as a critical, non-canonical target. A comprehensive synthesis of these interactions and their clinical implications is essential for advancing perioperative safety. This narrative review aims to provide a comprehensive analysis of the molecular interactions between common anesthetic agents and mitochondrial function, bridging the mechanisms of cellular bioenergetics with relevant clinical outcomes. A literature search was conducted across major databases, including PubMed, Scopus, and Web of Science, to synthesize and interpret findings from in vitro, in vivo, and clinical studies published between January 2000 and August 2025. Our synthesis reveals that anesthetics directly modulate the electron transport chain, leading to a dual-edged production of reactive oxygen species (ROS) that can be either protective (preconditioning) or damaging (oxidative stress). We find that agents exhibit distinct mitochondrial profiles: sevoflurane often confers protection, propofol shows dose-dependent toxicity linked to bioenergetic failure, and dexmedetomidine acts as a mito-protective adjunct. These interactions disrupt mitochondrial dynamics and can culminate in a "bioenergetic crisis" at the synapse, where energy demand is increased while mitochondrial ATP supply is compromised. Viewing anesthetics as potent mitochondrial modulators is crucial for the evolution of anesthesiology. This perspective shifts the paradigm towards personalized anesthetic strategies based on a patient's underlying mitochondrial vulnerability. We conclude that future research should focus on developing non-invasive biomarkers of mitochondrial health and creating "mito-sparing" anesthetic protocols to improve patient safety and long-term outcomes.